Nutrition
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Randomized Controlled Trial
Added bovine milk fat globule membrane in formula: Growth, body composition, and safety through age 2: An RCT.
The aim of this study was to assess the effects of an experimental formula (EF) with added whey protein-lipid concentrate (5 g/L; source of bovine milk fat globule membrane [bMFGM]) on growth, body composition, and safety through 24 mo of age in term infants. ⋯ During the first 2 y of life, infant formula with added bMFGM supports typical growth and safety compared with a standard formula.
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Randomized Controlled Trial Multicenter Study
Vitamin K2 as a potential therapeutic candidate for the prevention of muscle cramps in hemodialysis patients: A prospective multicenter, randomized, controlled, crossover pilot trial.
Muscle cramps occur in 33% to 78% of patients with dialysis. The etiology of muscle cramps is poorly understood, and no clear evidence-based prevention or treatment strategies exist. Improved interventions are urgently needed. The aim of this study was to investigate the effect of vitamin K2 in reducing the frequency and severity of muscle cramps in hemodialysis (HD) patients. ⋯ This pilot trial demonstrated that vitamin K2 supplementation could decrease the frequency, duration, and severity of muscle cramps in HD patients.
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Randomized Controlled Trial
Prickly pear juice consumption after fat intake affects postprandial heart rate variability but not traditional risk factors of cardiovascular disease in healthy men.
Prickly Pear (PP) fruit is proposed to have anti-atherosclerotic and anti-hyperglycemic effects. The aim of this study was to examine the effects of a single consumption of PP juice on modifiable blood and physiological markers of cardiovascular disease risk in healthy men using a postprandial hyperlipidemia model. ⋯ Consumption of PP (with high-fat muffin), did not alter traditional cardiovascular disease risk responses but rather markers of HRV, beyond an expected increase in glucose attributed to the carbohydrate content of the trials foods. Additionally, macronutrient content is important when understanding HRV responses to meals.
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Randomized Controlled Trial
One week of high-fat overfeeding alters bone metabolism in healthy males: A pilot study.
Short periods of excessive consumption of indulgent high-fat foods are common in Western society, but the effect this has on bone is unknown. The aim of this pilot study was to explore how a 7-d hyperenergetic, high-fat diet affects candidate biomarkers of bone metabolism. ⋯ A 7-d hyperenergetic, high-fat diet reduces a marker of bone formation but does not affect a marker of bone resorption. This pilot study suggested that short periods of excessive energy and fat consumption may detrimentally affect bone health.
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Randomized Controlled Trial Observational Study
Diet and mental health in pregnancy: Nutrients of importance based on large observational cohort data.
To determine associations between dietary intake and well-being in pregnancy. ⋯ Maternal nutrition and well-being are related during early pregnancy. Our findings suggest that fiber, magnesium, and particular B vitamins may be of importance for promoting positive mental well-being during pregnancy.