Journal of clinical anesthesia
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Spinal 2-chloroprocaine has pharmacokinetic advantages over low dose bupivacaine that make it a useful choice for ambulatory surgery.
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Neuraxial morphine does not have a protective effect on headache after unintentional dural puncture.
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Randomized Controlled Trial
Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial.
To assess the effect of different intraoperative blood pressure targets on the development of POCD and test the feasibility of a larger trial. ⋯ Intraoperative hypotension did not correlate with postoperative cognitive dysfunction or delirium occurrence in elderly patients undergoing general anesthesia for non-cardiac surgery. A multicenter randomized controlled trial is needed in order to confirm the effect of intraoperative blood pressure on the development of POCD.