Gastrointestinal endoscopy
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Gastrointest. Endosc. · Mar 2009
Randomized Controlled Trial Comparative StudyMidazolam with meperidine or fentanyl for colonoscopy: results of a randomized trial.
A combination of midazolam and opioid is usually used to achieve sedation and analgesia during colonoscopy. Two commonly used opioids are meperidine and fentanyl, but few studies have compared their efficacy. ⋯ The use of fentanyl in combination with low-dose midazolam results in significantly faster recovery from sedation compared with meperidine, without any apparent loss of analgesic effect.
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Gastrointest. Endosc. · Mar 2009
Randomized Controlled TrialCan wire-guided cannulation prevent post-ERCP pancreatitis? A prospective randomized trial.
Among the procedure-related factors associated with post-ERCP pancreatitis, selective cannulation of the common bile duct by insertion of a guidewire may be associated with fewer complications than conventional methods of cannulation with contrast injection to access the bile duct. However, the results of studies regarding the usefulness of wire-guided cannulation (WGC) are conflicting. ⋯ WGC is associated with a lower rate of post-ERCP pancreatitis. However, WGC may not prevent post-ERCP pancreatitis in patients with suspected SOD and unintentional PD guidewire cannulation.
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Gastrointest. Endosc. · Dec 2008
Randomized Controlled Trial Comparative StudyProspective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos).
Although prior studies evaluated the role of EUS and EGD for drainage of pancreatic pseudocysts, there are no randomized trials that compared the technical outcomes between both modalities. ⋯ When available, EUS should be considered as the first-line treatment modality for endoscopic drainage of pancreatic pseudocysts given its high technical success rate.
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Gastrointest. Endosc. · Sep 2008
Randomized Controlled Trial Comparative StudyNurse-administered propofol sedation compared with midazolam and meperidine for EUS: a prospective, randomized trial.
The utility of nurse-administered propofol sedation (NAPS) compared with midazolam and meperidine (M/M) for EUS is not known. ⋯ Compared with M/M, NAPS for an EUS offered a faster sedation induction and full recovery time, higher postprocedure patient satisfaction, and a quicker anticipated return to baseline function. Total costs were similar between the groups.
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Gastrointest. Endosc. · Aug 2008
Randomized Controlled Trial Comparative StudyA randomized, controlled, double-blind trial of the adjunct use of tegaserod in whole-dose or split-dose polyethylene glycol electrolyte solution for colonoscopy preparation.
Problems of compliance, quality, and safety of colon preparation regimens have prompted continued investigation with alternative forms of cleansing. ⋯ Tegaserod has a marginal effect on the quality of colonoscopy preparation when used as an adjuvant to PEG-E. The split-dose PEG-E was superior to the whole-dose PEG-E and resulted in better colon cleansing, adherence, and tolerance.