Lancet neurology
The most recent articles from:
Lancet Neurol
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Comparative Study
Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study.
Three subtypes of Alzheimer's disease (AD) have been pathologically defined on the basis of the distribution of neurofibrillary tangles: typical AD, hippocampal-sparing AD, and limbic-predominant AD. Compared with typical AD, hippocampal-sparing AD has more neurofibrillary tangles in the cortex and fewer in the hippocampus, whereas the opposite pattern is seen in limbic-predominant AD. We aimed to determine whether MRI patterns of atrophy differ between these subtypes and whether structural neuroimaging could be a useful predictor of pathological subtype at autopsy. ⋯ US National Institutes of Health (National Institute on Aging).
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Biography Historical Article
Xavier Montalban: a pioneer in understanding multiple sclerosis.