Respiratory physiology & neurobiology
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Respir Physiol Neurobiol · Nov 2009
ReviewAutonomic function following cervical spinal cord injury.
Spinal cord injury (SCI) is commonly associated with devastating paralysis. However, this condition also results in a variety of autonomic dysfunctions, primarily: cardiovascular, broncho-pulmonary, urinary, gastrointestinal, sexual, and thermoregulatory. SCI and the resultant unstable autonomic control are responsible for increased mortality from cardiovascular and respiratory disease among individuals with SCI. ⋯ Furthermore, similar relationships can exist between the level of SCI and function of other organs that are under autonomic control (bladder, bowel, sweat glands, etc.). It is also important to appreciate that high cervical injuries result in significant respiratory dysfunctions due to the involvement of the diaphragm and a larger portion of the accessory respiratory muscles. Early recognition and timely management of autonomic dysfunctions in individuals with SCI are crucial for the long term health outcomes in this population.