African health sciences
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African health sciences · Jun 2013
Global analysis of differential expressed genes in ECV304 Endothelial-like cells infected with human cytomegalovirus.
Human cytomegalovirus (HCMV) is a virus which has the potential to alter cellular gene expression through multiple mechanisms. ⋯ Several of these gene products might play key roles in virus-induced pathogenesis. These findings may help to elucidate the pathogenic mechanisms of HCMV caused diseases.
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African health sciences · Jun 2013
Alcohol consumption and cigarette smoking pattern among brothel-based female sex workers in two local government areas in Lagos state, Nigeria.
Alcohol and tobacco use are known risk factors for non communicable diseases especially among women. Brothel based female sex workers may be at increased risk of exposure to these two substances. ⋯ The prevalence of harmful alcohol use and cigarette smoking are very high among this group of female sex workers. Programs that address the use of these substances should be made available for these women.
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African health sciences · Jun 2013
Living with parents and risky sexual behaviors among preparatory school students in Jimma zone, South west Ethiopia.
Risky sexual behavior is any behavior that increases the probability of negative consequences associated with sexual contact. Family environment, peer influence, community factors and school attachment seem an important factor affecting sexual risk behavior and decision of in-school youths. ⋯ Alcohol consumption and religious visit were the major predictors of risky sexual behaviors. Therefore, Behavior change communication should consider family environment and other factors which predict risk sexual behaviors.
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African health sciences · Jun 2013
Randomized Controlled TrialAntiemetic effects of dexamethasone and ondansetron combination during cesarean sections under spinal anaesthesia.
Nausea and vomiting are frequently seen in patients undergoing cesarean section (CS) under regional anesthesia. We aimed to compare the antiemetic efficacy of ondansetron and dexamethasone combination with that of the use of each agent alone to decrease the incidence of post-delivery intraoperative nausea and vomiting (IONV) during CS under spinal anesthesia. ⋯ Single dose 4mg ondansetron, 8mg dexamethasone, or combined use of 8mg dexamethasone+4mg ondansetron, given intravenously is all effective agents for the control of postdelivery IONV. Combined use of dexamethasone and ondansetron for the same indication does not seem to increase the antiemetic efficacy.
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African health sciences · Jun 2013
24-Month adherence, tolerance and efficacy of once-a-day antiretroviral therapy with didanosine, lamivudine, and efavirenz in African HIV-1 infected children: ANRS 12103/12167.
There is no data on long-term benefit of once-a-day antiretroviral therapy (ART) with combination of DDI, 3TC and EFV to allow its use in future therapeutic strategies. ⋯ Given the limited number of antiretroviral drugs available in Africa and the inadequacy of laboratory monitoring in support program, once-a-day treatment and especially the DDI-based combination strategies could be an attractive operational option.