African health sciences
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African health sciences · Dec 2016
Prevalence and socioeconomic correlates of autism among children attending primary and secondary schools in south east Nigeria.
The objectives of the study were to determine the prevalence and socio-economic determinants of autism among children attending primary and secondary schools in South East, Nigeria. ⋯ The prevalence of autism was 2.9%; and the socio-economic characteristics of childhood autism in South East Nigeria are similar to those in other parts of the world.
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African health sciences · Dec 2016
Prevalence of suicidal ideation and attempt: associations with psychiatric disorders and HIV/AIDS in post-conflict Northern Uganda.
Research on the prevalence of suicidal ideation, attempt, and cormorbid psychiatric disorders in post-conflict areas is still limited. ⋯ The prevalence rate of suicide ideation and attempt indicate a major public health problem in post-conflict Northern Uganda. Effective public mental health programs that that target both suicidality and psychiatric co-morbodities will be vital. Special attention should be given to women in post conflict Northern Uganda.
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African health sciences · Dec 2016
Retinal nerve fibre layer thickness values and their associations with ocular and systemic parameters in Black South Africans.
To measure the retinal nerve fibre layer (RNFL) thickness values and investigate their associations with other parameters in healthy eyes of Black South Africans. ⋯ Mean RNFL thickness values and their associations established in this population may be of clinical value when assessing factors that influence this parameter and diagnosing diseases affecting it.
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African health sciences · Dec 2016
Glyceryl trinitrate is a novel inhibitor of quorum sensing in Pseudomonas aeruginosa.
Targeting quorum sensing is an alternative approach to antibiotics.Targeting quorum sensing-regulated virulence will disarm the pathogen without exerting pressure on its growth. As a result, emergence of resistance is avoided and the immune system can easily eradicate bacteria. ⋯ Glyceryl trinitrate can be an antivirulence agent in the treatment of Pseudomonas aeruginosa topical infections such as burn infections.
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African health sciences · Dec 2016
Chemical constituents of Cyperus rotundus L. and their inhibitory effects on uterine fibroids.
Xiang Fu (Cyperus rotundus L) enters the liver, spleen and triple warmer meridians, and has qi stagnation-removing, qi circulation-promoting, menstruation-regulating and pain-relieving effects. Besides, it can improve ovarian function, and has hypolipidemic, hypoglycemic and neuroprotective actions. ⋯ It concludes that amentoflavone has a significant inhibitory effect on uterine tumors in rats. Its mechanism may be by elevating Bax protein expression, down-regulating Bcl-2 expression, forming homodimers Bax/Bax, and reducing plasma estradiol and progesterone to promote apoptosis of uterine fibroid cells.