African health sciences
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African health sciences · Dec 2017
Sub-clinical middle ear malfunctions in elderly patients; prevalence, pattern and predictors.
Little is known about functioning of the middle ear with advancing age. ⋯ 21.5% of elderly Africans had subclinical abnormalities in their middle ear functioning, mostly with type AS tympanogram. Independent clinical predictors of S-MEM included previous head injury, diabetes, history of osteoarthritis of knee joints, and absent acoustic reflex.
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African health sciences · Dec 2017
The market dynamics of selective serotonin re-uptake inhibitors: a private sector study in South Africa.
The objective of this study was to analyse the market share of generic vs originator selective serotonin re-uptake inhibitors (SSRIs), and also compare market share of different SSRIs in the private health care sector in South Africa, over a period of 4 years. ⋯ In line with policies, generic SSRIs hold a larger volume of the market in the private sector in South Africa.
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African health sciences · Dec 2017
Analysis of SNPs of MC4R, GNB3 and FTO gene polymorphism in obese Saudi subjects.
The goal of this study was to analyze the association between the FTO rs17817449 (G>T), G protein beta3 subunit (GNB3) C825T and Melanocortin 4 receptor (MC4R) A822G single nucleotide polymorphism (SNP) with obesity in Saudi subjects. ⋯ The polymorphism of FTO gene rs17817449 and GNB3 gene rs5443 (C825T) may be a genetic determinant of obesity in Saudi population whereas impact of MC4R Asn274Ser change could not be detected.
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African health sciences · Dec 2017
Neurocalcin-delta: a potential memory-related factor in hippocampus of obese rats induced by high-fat diet.
Aberrant protein expression within the hippocampus has recently been implicated in the pathogenesis of obesity-induced memory impairment. ⋯ Our data demonstrates that the differential memory-related proteins were a reflection of the HF diet, but not potential factors in obesity proneness or obesity resistance. Furthermore, NCALD is proved to be a potential hippocampus-memory related factor related to obesity.
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African health sciences · Dec 2017
Case ReportsAn erroneous opinion on a cause of death in a forensic autopsy: a case report.
The quality of autopsies is always questioned in courts, especially in developing countries. Wrong decisions or misjudgments are undesirable in medicine, but they are very dangerous in forensic medicine. If a wrong opinion is given, either a culprit can be acquitted or an innocent person can be sentenced. Therefore, an expert opinion is always required before the announcement of a judgment. ⋯ An erroneous opinion was reached regarding cause and manner of death in this autopsy report.