African health sciences
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African health sciences · Dec 2020
The relationship between Vitamin D deficiency and polycystic ovary syndrome.
Vitamin D deficiency is frequently seen in patients with polycystic ovary syndrome (PCOS) and has been shown to exhibit multiple effects on the disease process. The purpose of this study was to investigate the role of vitamin D deficiency in complex PCOS pathophysiological pathways. ⋯ The study findings show that low 25(OH)D3 levels are associated with high androgen levels in women with PCOS. Vitamin D deficiency should be considered as an additional risk factor in the development of PCOS. We think that providing vitamin D supplementation for women from identified deficiency areas can reduce the risk of PCOS development.
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African health sciences · Dec 2020
The relationship between sleep quality and dyspnoea severity in patients with COPD.
This study aimed to determine sleep quality, frequency and severity of dyspnoea in COPD patients and to evaluate the relationship between dyspnoea severity and sleep quality. ⋯ It was concluded that the majority of COPD patients had moderate or poor sleep quality and dyspnoea. As dyspnoea severity increases, sleep quality decreases.
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African health sciences · Dec 2020
Combating female genital mutilation in Northeast (Horn) Africa and its challenges.
This article investigates the practice of female genital mutilation as a long-held custom in the countries of Northeast Africa, known as Horn of Africa, where many women in rural and urban areas are faced with different physical and psychic consequences in their future lives. ⋯ This study reveals the Health education based on behavioral change. In doing so, the unity of policies between regional and international actors along with attracting the support of tribal elites is also needed.
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African health sciences · Dec 2020
Evaluation of MRI Artifact in some selected centers in Kano Metropolis, Nigeria.
Magnetic Resonance Imaging (MRI) artifacts can occur due to hardware or software related problems, human physiologic phenomenon or physical restrictions. Careful study design and scanning protocols can prevent certain artifacts from occurring, but some are unavoidable. ⋯ In Kano metropolis the most encountered MRI artifact was the motion-induced artifact and thoracic spine MRI had the highest number of artifacts. The artifacts had a negative effect on image quality.
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African health sciences · Dec 2020
Improved antimalarial activity of caprol-based nanostructured lipid carriers encapsulating artemether-lumefantrine for oral administration.
Artemether and lumefantrine display low aqueous solubility leading to poor release profile; hence the need for the use of lipid-based systems to improve their oral bioavailability so as to improve their therapeutic efficacy. ⋯ This study has shown the potential of caprol-based NLCs for significant improvement in oral bioavailability and hence antimalarial activity of poorly soluble artemether and lumefantrine. Importantly, this would improve patient compliance due to decrease in dosing frequency as a sustained release formulation.