African health sciences
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African health sciences · Sep 2021
Prognostic significance of the preoperative neutrophil-to-lymphocyte ratio patients with giant cell tumor of bone.
To evaluate the prognostic significance of neutrophil-to-lymphocyte ratio (NLR) in giant cell tumor of bone (GCT). ⋯ Our findings showed that NLR is a new and promising inflammation-based prognostic factor in GCT patients.
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African health sciences · Sep 2021
Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study.
TB/HIV co-infection is a major public health problem in many parts of the world. But the prevalence of co-infection was varies among countries.This study was designed to assess prevalence of TB/HIV co-infection and to determine its factors. ⋯ The prevalence of TB among HIV patients was high and predicted by marital, education status, weight, CD4 cell count and WHO clinical stage III.
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African health sciences · Sep 2021
Prevalence of sickle cell trait and its association to renal dysfunction among blood donors at University of Medical Sciences Teaching Hospital, Ondo, Nigeria.
Prospective blood donors are routinely screened for blood borne infections but medical illnesses and haemoglobin genotype are overlooked despite a high prevalence of haemoglobin AS among Nigerian donors. ⋯ The prevalence of sickle cell trait among Nigerian blood donors is high. There is no significant difference in the renal function status of blood donors with SCT and normal haemoglobin genotype.
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African health sciences · Sep 2021
Social support as a correlate of depression among people living with HIV and AIDS in Nigeria.
Depression is a highly prevalent mental disorder among PLHIV, whilst social support is important in disease prevention, health promotion, therapeutic measure especially for PLHIV. ⋯ PLHIV have satisfactory social support, especially from family not residing in the same household and emotional social support from friends. Analyses identified knowledge gaps in the community regarding the social support received by PLHIV and their depression symptoms.
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African health sciences · Sep 2021
SRY and NR5A1 gene mutation in Algerian children and adolescents with DSD and testicular dysgenesis.
In humans, sex determination and differentiation is genetically controlled. Disorders of sex development (DSD) result in anomalies of the development of the external and internal genitalia. Variants in transcription factors such as SRY, NR5A1 and SOX9, can cause changes in gonadal development often associated with ambiguity of the external genitalia. ⋯ The absence of mutations in these genes suggests that there are others genes playing an important role in sex development and differentiation.