African health sciences
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African health sciences · Mar 2023
Analysis of the proportion of university teaching hospital gastric cancer data included in the Zambia national cancer registry.
The exact prevalence of gastric cancer in Zambia is unknown. The aim of this study was to determine the proportion of gastric cancer cases seen at the largest hospital in Zambia, whose records were included in the Zambia National Cancer Registry (ZNCR). ⋯ Data on gastric cancer reported in the ZNCR are an underestimate of the true disease burden and there is need to strengthen data collection strategies for gastric cancer in Zambia.
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African health sciences · Mar 2023
Case ReportsTakayasu arteritis, an atypical presentation as chronic kidney disease.
Takayasu arteritis, also known as "pulseless disease" usually affects major vessels like aorta and its branches, pulmonary arteries, and renal arteries. Hypertension is the common presentation. Chronic kidney disease involvement is less common. ⋯ We discuss a case of a young female who presented with accelerated hypertension with chronic kidney disease with preserved peripheral pulses. The diagnosis was confirmed by Computed tomography aortic angiogram, which showed diffuse circumferential thickening, multifocal ectasia, and aneurysmal dilatation with few saccular outpouchings of the aortic arch, descending thoracic and abdominal aorta (Type V). The patient was treated with steroids, antihypertensives, antiplatelet, and hemodialysis.
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African health sciences · Mar 2023
Effect of inter-pregnancy interval on serum ferritin, haematocrit and pregnancy outcome in Ilorin, Nigeria.
Available information remains limited on inter-pregnancy interval (IPI) and its effect on maternal health and pregnancy outcome. ⋯ Low serum ferritin, haematocrit and adverse neonatal outcomes were associated with SIPI.
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African health sciences · Mar 2023
CD4/CD8 Ratio could be predictor of burden hepatocellular carcinoma in Egyptian chronic hepatitis C after combined sofosbuvir and daclatasvir therapy.
During the first years of the use of direct acting Hepatitis C antiviral drugs (DAAS), several studies reported a possible correlation between this new era of treatment and an increased risk of Hepatocellular carcinoma (HCC). Its development could possibly be favored by the changes in the immunological milieu and the different cellular behavior after eradication of HCV infection with them. For this reason, this study aimed to address the immunological effect of DAAS. ⋯ HCV treatment by DAAS produces significant decrease in T helper, T cytotoxic cells in CHC patients at the end of therapy. 26.6% developed focal HCC with independent CD4/CD8 predictor for burden malignancy. Further large extended population study is needed for clarify this concern.
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African health sciences · Mar 2023
A validation of adult suicidal ideation questionnaire among Nigerian University students.
To prevent completed suicide among young adults in the university, assessment of suicidal ideation should be encouraged. This study aims to investigate the reliability, exploratory factor analysis, and validity of adult suicidal ideation questionnaire among Nigerian university students. ⋯ This study concludes that ASIQ has slight modification from the original version among young adults in Nigeria. The scale is reliable and valid but as a 22-item instrument on a 5-point Likert scale.