African health sciences
-
African health sciences · Mar 2023
Neonatal pain perception, management and review of practises among medical workers in Nigeria newborn units.
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. The perception of pain is variable and knowledge may not match practise. ⋯ Perception of pain was high but did not match knowledge and practice of NPM. Formal education on NPM was lacking in the training of HCW.
-
African health sciences · Mar 2023
Imaging of developmental delay in black African children: A hospital-based study in Yaoundé-Cameroon.
The purpose of this study was to describe the anomalies observed on imaging for developmental delay in black African children. ⋯ In our context, there is a high prevalence of organic anomalies in the imaging of psychomotor delay, which were dominated by cerebral atrophy secondary to hypoxic ischemic events.
-
African health sciences · Mar 2023
Clinicopathological, immunohistochemical, molecular-genetic and risk profiles of gastrointestinal stromal tumors in a cohort of Sudanese patients.
Determining the risk of malignant behaviour and mutational status of gastrointestinal stromal tumours (GISTs) guide the management decision and allow optimal individualized patient treatment. ⋯ Sudanese patients with GIST tend to present late. Nearly half of them correspond to the malignant/high-risk category. The frequency of KIT mutations (79.31%) is in line with the literature.
-
African health sciences · Mar 2023
Cost-effectiveness of dolutegravir vs. efavirenz-based combined antiretroviral therapies in HIV-infected treatment-naive patients in a Nigerian treatment centre.
Dolutegravir (DTG) based antiretroviral therapy (ART) has largely replaced Efavirenz (EFV) based therapy as the preferred first-line regimen in the treatment of adults with HIV. This study was carried out to evaluate the comparative cost-effectiveness of DTG and EFV-based ART in HIV-infected treatment-naïve patients in a treatment centre in Nigeria. ⋯ Efavirenz based regimen had higher treatment effectiveness than DTG-based regimen in treatment-naive patients after initiating treatment in a short term. Compared to EFV, DTG-based regimen is cost-effective in the management of treatment naïve HIV patients.
-
African health sciences · Mar 2023
Predictors of mortality and survival probability distribution among patients on tuberculosis treatment in Vihiga County, Kenya.
Tuberculosis (TB) related mortality remains a serious impediment in ending TB epidemic. ⋯ Risk of TB mortality is high and is attributable to comorbidities, severe illness, HIV and smoking. Causes and conditions contributing to TB mortality are multifaceted but modifiable. Improving TB/HIV care could reduce mortality in this setting.