African health sciences
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African health sciences · Mar 2023
Genetic diversity of Plasmodium falciparum among asymptomatic pregnant women on intermittent preventive treatment with sulfadoxine-pyrimethamine in Nigeria.
This study investigated the genetic diversity of Plasmodium falciparum among asymptomatic pregnant women on intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-Sp) in Osogbo, southwest Nigeria. Blood sample was obtained from consenting pregnant women attending antenatal clinics. Microscopy and Polymerase chain reaction (PCR) were employed to diagnose and analyse genetic diversity. ⋯ Nine alleles were detected with glurp gene, presenting with the highest monoclonal and the lowest polyclonal infection. The multiplicity of infection (MOI) of 1.5, 1.8, and 1.2 were obtained for msp-1, msp-2 and glurp genes. In light of the high P. falciparum genetic diversity among pregnant women on IPT-Sp in this study, additional strategies for preventing and controlling malaria in pregnancy might be required.
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African health sciences · Mar 2023
Establishment of a urogynecology cadaver-based hands-on workshop.
It is important to train gynecologists and urologists on the principles of urogynecological surgery. ⋯ Our course was highly valued by the participants who came from all over the Middle East. The course was enjoyable and achieved its objectives while the participants gained new knowledge and surgical skills.
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African health sciences · Mar 2023
Laboratory characteristics among patients with COVID-19: a single-center experience from Khartoum, Sudan.
COVID19 is associated with a number of laboratory characteristics and changes with different levels of prognostic significance. We report changes in lab findings between severe and non-severe COVID-19 in patients that had molecular testing of nasopharyngeal swabs in Khartoum, Sudan. ⋯ The laboratory findings of CBC, D-dimer and CRP provide an essential contribution to predicti COVID-19 severity and prognosis.
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African health sciences · Mar 2023
Intimate partner violence and child loss: an evaluation of 7 sub-Saharan African countries.
Intimate partner violence (IPV) and child loss disproportionately affect women in sub-Saharan Africa (SSA). Little research has examined the relationship between IPV and child loss in SSA. ⋯ These results suggest that women who experienced all types of and cumulative exposure to IPV may be more likely to lose a child in SSA.
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African health sciences · Mar 2023
Investigation of antiviral substances in Covid 19 by Molecular Docking: In Silico Study.
This paper aimed to investigate the antiviral drugs against Sars-Cov-2 main protease (MPro) using in silico methods. ⋯ Bictegravir, remdevisir and lopinavir drugs showed very good results compared to the N3 inhibitor. Therefore, they could be inhibitory in the Sars Cov-2 Mpro target.