African health sciences
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African health sciences · Mar 2023
Investigation of antiviral substances in Covid 19 by Molecular Docking: In Silico Study.
This paper aimed to investigate the antiviral drugs against Sars-Cov-2 main protease (MPro) using in silico methods. ⋯ Bictegravir, remdevisir and lopinavir drugs showed very good results compared to the N3 inhibitor. Therefore, they could be inhibitory in the Sars Cov-2 Mpro target.
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African health sciences · Mar 2023
Factors associated with intention to smoke cigarettes among never smoker school going adolescents in Zambia.
Cigarette smoking intention is a strong predictor of cigarette smoking initiation. There is limited data on predictors of cigarette smoking intentions among adolescents in developing countries. ⋯ Having smoking parents, smoking friends or around people who smoke in public places were associated with cigarette smoking intentions among adolescents.
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African health sciences · Mar 2023
Prevalence of gastrointestinal bleeding and frequency of selected predictors of mortality on the medical emergency ward at Mulago hospital.
There was no data on the prevalence of Gastrointestinal bleeding (GI) among patients admitted on the emergency ward at Mulago hospital. This was partly because the medical records were not adequately completed as designed. ⋯ The prevalence of GI bleeding on the medical emergency ward of Mulago hospital is high. This calls for strategies for resuscitative management of this life-threatening medical emergency. Among the selected predictors of mortality, tachycardia was most frequent followed by hypotension. These should always be assessed in a patient with GI bleeding and resuscitative measures with blood transfusion and intravenous fluids undertaken to correct them.
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African health sciences · Mar 2023
Case control study of CD4 cell count and some haematological parameters among hepatitis and non-hepatitis B patients in Oyo State, South-west, Nigeria.
Hepatitis B virus HBV infection is a major cause of chronic liver disease worldwide. CD4 count and haematological parameters (HPs) could be used to monitor the health status of hepatitis B (HB) individuals. This study aimed at assessing levels of CD4 count and some HPs among sufferers of HB patients and controls. ⋯ There were no significant differences between the values of the CD4 count and hematological parameters among HB subjects in this study. There is need for future studies to detect changes in CD4 count and other HPs in HB patients to increase options of screening for immunological changes during management.
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African health sciences · Mar 2023
Physician perspectives on the DNR order in Turkey: A survey of physicians in Internal Medicine.
Do not resuscitate (DNR) is a controversial ethico-legal issue and there is no legal regulation in Turkey. Evaluating the physicians' views on DNR is critical to the current problems and contributes to legal regulation. ⋯ It is necessary to establish legal regulations on DNR and implement residency training programs that will ensure the continuous professional development of physicians.