African health sciences
-
African health sciences · Sep 2023
Assessment of the relationship between miR-499C/T (rs3746444) polymorphism and lung carcinoma in Iranian population; a case-control study.
Lung carcinoma is characterized by uncontrollable division of respiratory system cells with detrimental and lethal consequences on human health. Critical roles of microRNAs (miR) are scientifically approved in biological and pathological pathways, such as the role of miR-499 (rs3746444) in lung carcinomas. Thus, in this case-control investigation, we aimed to assess the probable relationship between miR-499C/T variant and the occurrence of lung carcinoma in Iranian population for the first time. ⋯ In this study, a possible relationship among miR-499C/T polymorphism and lung carcinoma was detected in Iranian population. Since this study was conducted for the first time, thus other supplementary assessments are needed for definite conclusion.
-
African health sciences · Sep 2023
A cross-sectional study of prevalence and predictors of risky sexual behavior among school-going adolescents in Mbarara municipality, Uganda.
Adolescents in Sub-Saharan Africa are at a greater risk of experiencing the adverse consequences of risky sexual behavior such as unwanted pregnancy and school drop-out than adolescents from other regions. ⋯ Most of the participants were not sexually active, however, among the sexually active students, more than half engaged in risky sexual behavior. This finding suggests the need to introduce comprehensive sex education with a focus on safe sex practices in secondary schools in Uganda.
-
African health sciences · Sep 2023
The effect of the Covid-19 pandemic on Tuberculosis (TB) case notification in Ogun State, Nigeria.
COVID-19 pandemic has resulted in disruptions in delivery of Tuberculosis services especially, in resource-limited settings. Provisional data by the WHO from 84 countries indicates that about 1.4 million fewer people received care for tuberculosis in 2020 than in 2019. This study assessed the effect of COVID-19 pandemic on tuberculosis case notification rates in Ogun state, Nigeria. ⋯ Total TB cases notified in Ogun state increased during the covid-19 pandemic. There was significant decline in TB cases during the lockdown but an increase in proportion of TB cases notified by private facilities demonstrating that private facilities can withstand disruptions to TB case notifications due to the Covid-19 pandemic.
-
African health sciences · Sep 2023
Decision to delivery interval, maternal and fetal outcomes in emergency caesarean sections in a tertiary teaching hospital, Dar es salaam, Tanzania.
Emergency caesarean section (CS) answers the question on how soon the procedure should be performed. Maternal and fetal outcomes deteriorate when decision to delivery interval (DDI) exceeds 75 min. This study aimed at determining the DDI, Maternal and fetal outcomes in CS categories at Muhimbili National Hospital (MNH). ⋯ The proportions of adverse maternal and fetal outcome were high when DDI was ≥ 75 min. Improving triage of the patients according to their urgency is crucial in reducing prolonged DDI.
-
African health sciences · Sep 2023
Correlates of somatic symptom disorder among internally displaced persons in Ogoja displacement settlements, Nigeria: a cross-sectional study.
Experiences of displacement have been associated with the prevalence of mental health disorders owing to certain factors. ⋯ The findings suggest that the high prevalence of the studied outcome is related to several stressors and events among Internally displaced persons. Evidence-based mental health support efforts by different bodies in creating and routinely arranging mental health clinical interventions for this population is recommended.