African health sciences
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African health sciences · Sep 2023
Epidemiological features of tuberculosis in the Middle East and North Africa from 1990 to 2019: results from the global burden of disease Study 2019.
Tuberculosis (TB) is a preventable and curable disease, although, it still causes more than one million deaths annually. Therefore, the aim of this study was to measure the epidemiological status and the burden of TB in the Middle East and North Africa (MENA) countries. ⋯ TB has continued to decrease in prevalence, incidence, death, and DALYs rates in the MENA region, although, nowadays with the COVID-19 pandemic, societies may face more challenges for TB prevention, detection, treatment, and rehabilitation.
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African health sciences · Sep 2023
Service delivery inaccessibility as a predictor of teenage pregnancy in South Africa.
With the onset of the South African democracy in 1994 it was hoped that many social inequalities would be addressed urgently. However, studies have shown that service delivery inaccessibility remains a challenge and investigating the social implications of such injustices remains important. ⋯ Findings highlight the need to guarantee universal service delivery urgently not only for development, but also to prevent adolescent pregnancy. Furthermore, the findings present evidence of structural factors driving adolescent pregnancy in South Africa, which renders continued cycles of poverty, injustice and early pregnancy amongst the majority of Blacks.
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African health sciences · Sep 2023
Assessment of risk factors associated with multi-drug resistant tuberculosis (MDR-TB) in Gulu regional referral hospital.
Multi-drug resistant tuberculosis (MDR-TB) is increasingly recognized as emerging infectious disease of public health concern. Globally, 206030 people were diagnosed with MDR-TB in 2019, representing a 10% increase from 186883people who had it in 2018. In Uganda, the prevalence of MDR among new TB cases is 4.4% and 17.7% among previously treated TB cases. ⋯ There is high prevalence of drug resistance among patients attending TB treatment at the facility.
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African health sciences · Sep 2023
Malignancy-related mir-210, mir-373 and let-7 levels are affected in iron deficiency anemia.
Hypoxia is the hallmark of iron deficiency anemia (IDA) and in hypoxic environment, significant changes are observed in malignancy-related microRNAs (miRNA). Our aim is to examine whether there is any difference in the levels of miR-210, miR-373 and let-7, which are directly related to malignancies in patients with IDA. ⋯ Plasma miR-210 expression was significantly up-regulated and miR-373 and let-7 expression was down-regulated, though insignificantly, in IDA group.
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African health sciences · Sep 2023
Meta AnalysisComparison of iron isomaltoside ferumoxytol with iron sucrose for iron deficiency anemia: a meta-analysis of randomized controlled trials.
The efficacy of iron isomaltoside ferumoxytol versus iron sucrose to treat iron deficiency anemia remains controversial. We conduct this meta-analysis to explore the influence of iron isomaltoside ferumoxytol versus iron sucrose on iron deficiency anemia. ⋯ Iron isomaltoside ferumoxytol showed comparable efficacy to iron sucrose for the treatment of iron deficiency anemia.