Neurocritical care
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Randomized Controlled Trial Multicenter Study
Impact of systemic inflammatory response syndrome on vasospasm, cerebral infarction, and outcome after subarachnoid hemorrhage: exploratory analysis of CONSCIOUS-1 database.
Systemic inflammatory response syndrome (SIRS) may develop after aneurysmal subarachnoid hemorrhage (SAH). We investigated factors associated with SIRS after SAH, whether SIRS was associated with complications of SAH such as vasospasm, cerebral infarction, and clinical outcome, and whether SIRS could contribute to a difference in outcome between patients treated by endovascular coiling or neurosurgical clipping of the ruptured aneurysm. ⋯ SIRS was associated with poor outcome but not angiographic vasospasm, DIND, or cerebral infarction after SAH in the CONSCIOUS-1 data. There was no support for the notion that neurosurgical clipping is associated with a greater risk of SIRS than endovascular coiling.
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Prognostication for survivors of cardiac arrest is a frequent challenge to neurologists. Our aim was to determine whether the FOUR (Full Outline of UnResponsiveness) score is an accurate predictor of outcome in patients after cardiac arrest and to compare its performance to the Glasgow Coma Scale (GCS). ⋯ The FOUR score, a simple clinical tool, is an accurate predictor of outcome in patients surviving cardiac arrest.