Interactive cardiovascular and thoracic surgery
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Interact Cardiovasc Thorac Surg · Sep 2012
Comparative StudyUse of prothrombin complex concentrate for excessive bleeding after cardiac surgery.
Prothrombin complex concentrates (PCCs) are sometimes used as 'off label' for excessive bleeding after cardiopulmonary bypass (CPB). The main objective of this study was to retrospectively evaluate the clinical and biological efficacy of PCC in this setting. ⋯ Administration of low-dose of PCC significantly decreased postoperative bleeding after CPB.