JPEN. Journal of parenteral and enteral nutrition
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JPEN J Parenter Enteral Nutr · Feb 2017
Multicenter StudyValidation of Bedside Ultrasound of Muscle Layer Thickness of the Quadriceps in the Critically Ill Patient (VALIDUM Study).
In critically ill patients, muscle atrophy is associated with long-term disability and mortality. Bedside ultrasound may quantify muscle mass, but it has not been validated in the intensive care unit (ICU). Here, we compared ultrasound-based quadriceps muscle layer thickness (QMLT) with precise quantifications of computed tomography (CT)-based muscle cross-sectional area (CSA). ⋯ Our results suggest that QMLT alone with our current protocol may not accurately identify patients with low muscle mass.
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JPEN J Parenter Enteral Nutr · Jan 2016
Multicenter Study Observational StudyClinical Outcomes Related to Protein Delivery in a Critically Ill Population: A Multicenter, Multinational Observation Study.
Optimal intake of energy and protein is associated with improved outcomes, although outcomes relative to protein intake are very limited. Our purpose was to evaluate the impact of prescribed protein delivery on mortality and time to discharge alive (TDA) using data from the International Nutrition Survey 2013. We hypothesized that greater protein delivery would be associated with lower mortality and shorter TDA. ⋯ Achieving at least 80% of prescribed protein intake may be important to survival and shorter TDA in ICU patients. Efforts to achieve prescribed protein intake should be maximized.
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JPEN J Parenter Enteral Nutr · Aug 2015
Multicenter StudyImplementing the PEP uP Protocol in Critical Care Units in Canada: Results of a Multicenter, Quality Improvement Study.
Previous studies have documented widespread iatrogenic underfeeding in intensive care unit (ICU) patients. In an experimental setting, we demonstrated the safety and efficacy of a novel enteral feeding protocol designed to overcome the main barriers to adequate delivery of enteral nutrition (EN), the Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol (PEP uP protocol). The purpose of this article is to describe our experience with implementing this feeding protocol under "real-world" settings in Canada. ⋯ In the real-life setting, the PEP uP protocol can improve the delivery of EN to critically ill patients.
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JPEN J Parenter Enteral Nutr · May 2015
Multicenter StudyPrevalence, risk factors, clinical consequences, and treatment of enteral feed intolerance during critical illness.
We aimed to determine the incidence of enteral feed intolerance and factors associated with intolerance and to assess the influence of intolerance on nutrition and clinical outcomes. ⋯ Intolerance occurs frequently during EN in critically ill patients and is associated with poorer nutrition and clinical outcomes.