Revista da Associacao Medica Brasileira (1992)
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To present scientific evidence based on a systematic review of the literature (PRISMA), aiming to systematize evidence of the ototoxic effects of hydroxychloroquine (HCQ). ⋯ The studies reported possible ototoxicity of HCQ. Audiovestibular changes, such as hearing loss, peripheral vestibular syndrome, and tinnitus were evidenced in patients submitted to HCQ. The improvement in the audiological examinations and the regression in the vestibular syndrome after stopping the treatment with HCQ are strong arguments in favor of the ototoxicity caused by this medication. However, there are still divergences about the relationship between ototoxic effects and the use of HCQ.
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Rev Assoc Med Bras (1992) · Jan 2021
Hyperglycemia in pregnancy: sleep alterations, comorbidities and pharmacotherapy.
To investigate sleep alterations and associated factors in pregnant diabetic women (n=141). ⋯ Our study originally shows that poor sleep quality and excessive daytime sleepiness are frequent in diabetic pregnancy due to different etiologies. Interestingly, only in gestational diabetes mellitus, metformin therapy and higher parity were associated with poor sleep quality.
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Rev Assoc Med Bras (1992) · Jan 2021
Clinician's perspective regarding medication adherence in patients with obstructive lung diseases and the impact of COVID-19.
Failure to achieve high levels of medication adherence in obstructive lung diseases is a major cause of uncontrolled disease. The purpose of this study is to reveal clinicians' opinions on the level of patient adherence and the change in adherence during the COVID-19 pandemic. ⋯ Adherence to medication is not at the desired levels in patients with obstructive lung diseases. However, when faced with a serious health threat, such as the COVID-19 pandemic, patients realize the severity of their illness and begin using their treatments more regularly.
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Rev Assoc Med Bras (1992) · Jan 2021
Limited cardiopulmonary capacity in patients with liver cirrhosis when compared to healthy subjects.
The present study compared cardiorespiratory capacity between cirrhotic patients and healthy subjects. ⋯ Based on these findings, it is possible to conclude that liver cirrhosis can compromise the patients' quality of life, mainly by inducing metabolic alterations which can impair functional capacity and lead to a sedentary lifestyle.
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Rev Assoc Med Bras (1992) · Jan 2021
Evaluation of cardiac parameters between survivors and nonsurvivors of COVID-19 patients.
The present study compares the cardiac parameters of the survivor and nonsurvivor patients with COVID-19 infection. ⋯ Advanced age and increased levels of high-sensitivity troponin, creatine kinase MB, and myoglobin were found to be associated with mortality.