Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Jul 2021
Observational StudySurvival outcome of pulmonary metastasectomy among the patients with colorectal cancers.
Pulmonary metastasectomy for the treatment of metastatic colorectal cancer is essential, but high ranked evidence of survival benefit is lacking. Here, we aimed to examine the prognostic factors after pulmonary metastasectomy in patients with colorectal cancer. ⋯ Pulmonary metastasectomy was associated with significantly long-time survival rates in mCRC (43 months of DFS and 55 months of OS). The second relapse occurred in 25 (75.7%) patients, with isolated lung metastases in nearly half of the patients (45.5%). Therefore, lung metastases in mCRC were unique and a multidisciplinary team including a thoracic surgeon should manage these patients.
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Rev Assoc Med Bras (1992) · Jul 2021
Observational StudyClinical evolution of a severe asthmatics group in the use of immunobiological therapy in a Brazilian Public Hospital.
A small portion of the asthmatic population (3.6%) has severe asthma (SA), presenting high morbimortality rates and demanding more financial resources than other asthmatic populations. The use of immunobiological therapy is an effective tool in controlling symptoms, decreasing the number of exacerbations, and reducing the use of systemic corticosteroids in these patients. In Brazil, epidemiological data regarding this asthmatic population using immunobiologicals and their evolution are scarce. ⋯ The use of omalizumab and mepolizumab as additional therapy in SA provided a significant improvement in the ACT and allowed the dose reduction of systemic corticosteroids, without significant improvement in FEV1 and in the frequency of severe exacerbations.
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Rev Assoc Med Bras (1992) · Jul 2021
The timing of micro-TESE: what is the ideal age for male and female partner to bring a child to home?
The aim of this study was to analyze the results of microsurgical testicular sperm extraction (micro-TESE) and investigate the potential factors that may affect the successful sperm retrieval and timing of micro-TESE. ⋯ The fertility decreased by both male and female age and for men with NOA. The early visit to doctor seemed to have positive effect.