Journal of thrombosis and haemostasis : JTH
-
J. Thromb. Haemost. · Jun 2014
Improving prediction of recanalization in acute large-vessel occlusive stroke.
Recanalization in acute ischemic stroke with large-vessel occlusion is a potent indicator of good clinical outcome. ⋯ Acute endovascular treatment is the single most important factor promoting recanalization in acute ischemic stroke. The presence of extracranial vessel stenosis or occlusion decreases recanalization rates. In patients with intracranial occlusions, higher NIHSS score and ASPECTS and normal vigilance facilitate recanalization. Clinical use of these predictors could influence recanalization strategies in individual patients.
-
J. Thromb. Haemost. · Jun 2014
Associations of pentraxin 3 with cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis.
Pentraxin 3 (PTX3) is probably a specific marker of vascular inflammation. However, associations of PTX3 with cardiovascular disease (CVD) risk have not been well studied in healthy adults or multi-ethnic populations. We examined associations of PTX3 with CVD risk factors, measures of subclinical CVD, coronary artery calcification (CAC) and CVD events in the Multi-Ethnic Study of Atherosclerosis. ⋯ In these apparently healthy adults, PTX3 was associated with CVD risk factors, subclinical CVD, CAC and incident coronary heart disease events independently of CRP and CVD risk factors. These results support the hypothesis that PTX3 reflects different aspects of inflammation than CRP, and may provide additional insights into the development and progression of atherosclerosis.
-
J. Thromb. Haemost. · Jun 2014
Blood glucose as a marker of venous thromboembolism in critically ill children.
The ability to predict the development of venous thromboembolism is highly desirable. ⋯ Hyperglycemia is associated with venous thromboembolism in critically ill non-diabetic children. Maximum blood glucose is a potential predictor of venous thromboembolism in this population.