Brazilian journal of otorhinolaryngology
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Braz J Otorhinolaryngol · Jul 2009
Distortion-product otoacoustic emissions and auditory brainstem responses sensitivity assessment in cisplatin-induced ototoxicity in rats.
Cisplatin (cis-diamminedicloroplatinum) is an antineoplastic drug used in the treatment of a variety of cancers, especially head-and-neck cancer. Its ototoxicity, however, has been noted as a common side-effect which limits its use and causes significant morbidity. ⋯ In rats, BERA was more sensitivity than DPOAE at detecting cisplatin-induced ototoxicity in rats considering different doses and means of administration.
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Braz J Otorhinolaryngol · Mar 2009
Randomized Controlled TrialTopical use of adrenaline in different concentrations for endoscopic sinus surgery.
The ideal adrenaline concentration remains unknown. ⋯ We favor the use of topical adrenalin 1:2,000 due to a clear superiority in hemostasis. Further investigation is needed to corroborate our findings.
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Braz J Otorhinolaryngol · May 2008
Review Case ReportsMultiple-sited amyloidosis in the upper aerodigestive tract: case report and literature review.
There are some reports of localized amyloidosis in the larynx, an entity that corresponds to one percent of all benign tumors of this region. However, there are only two cases of amyloidosis in the Waldeyer's ring 6, 13, 14. We hereby describe a rare case of amyloidosis in areas not associated with the upper aero-digestive tract: tonsil pillar, rhinopharynx, supraglottis and glottis, without visible continuity of amyloid tissue. We will also discuss post-operative follow up with severe dysphagia.
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Braz J Otorhinolaryngol · May 2008
Randomized Controlled TrialAntibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study.
Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population. ⋯ considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.