The Journal of bone and joint surgery. American volume
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J Bone Joint Surg Am
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J Bone Joint Surg Am · Aug 2018
Meta AnalysisRisk Factors and Pooled Rate of Prolonged Opioid Use Following Trauma or Surgery: A Systematic Review and Meta-(Regression) Analysis.
Prolonged use of opioids initiated for surgical or trauma-related pain management has become a global problem. While several factors have been reported to increase the risk of prolonged opioid use, there is considerable inconsistency regarding their significance or effect size. Therefore, we aimed to pool the effects of risk factors for prolonged opioid use following trauma or surgery and to assess the rate and temporal trend of prolonged opioid use in different settings. ⋯ Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.