Acta neurochirurgica
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Acta neurochirurgica · Feb 2011
Case ReportsEndarterectomy for asymptomatic carotid artery stenosis under local anaesthesia.
In this article, we present our experience with such operations performed under local anaesthesia. ⋯ We have achieved acceptable morbidity and mortality rates (1.8%) according to the parameters set by previous studies such as Asymptomatic Carotid Atherosclerosis Study and Asymptomatic Carotid Stenosis Trial as well as American Heart Association and European Stroke Organisation guidelines. All surgeries were done under local anaesthesia. Shunts were inserted in 22 cases (5.68%).
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Acta neurochirurgica · Feb 2011
Letter Biography Historical ArticleRoald Dahl's contribution to neurosurgery: the Wade-Dahl-Till shunt.
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Acta neurochirurgica · Feb 2011
Time course of heme oxygenase-1 and oxidative stress after experimental intracerebral hemorrhage.
Heme oxygenase-1 (HO-1), the rate-limiting enzyme for heme catabolism and iron production, its role in intracerebral hemorrhage (ICH) is controversial. The study was to investigate correlations between brain oxidative injury and HO-1 after experimental ICH. ⋯ HO-1 has both antioxidant and prooxidant properties in ICH. The early upregulation of HO-1 possibly fit with the events and be protective against oxidative stress, whereas its overexpression in the late stages may result in its dysfunction and be toxic. So it should be prudent to intervene ICH with the inhibitor/activator of HO-1.