Clinics
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Gastric Cancer (GC) was the third highest mortality rate among malignant tumors. Currently, no specific treatment is utilized to prevent the progression of GC. The detailed mechanism of GC was still elusive and this study aimed to clarify the mechanism of GC occurrence and development. ⋯ CST1 can promote the gastric cancer process by targeting the AKT pathway.
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The study was to investigate circRBM33 in septic acute lung injury (ALI). ⋯ CircRBM33 improves ALI in septic mice by targeting the miR-15a-5p/EZH1 axis.
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Sevoflurane (Sev) is an inhalational anesthetic for surgical procedures where it can trigger cognitive dysfunction and neuronal apoptosis. Gyosaponin (GpS) was studied for its effects on brain morphology and cognitive behaviors in Sev-anesthetized rats. ⋯ GpS ameliorates Sev-induced neurotoxicity and cognitive dysfunction by modulating the PI3K/Akt/mTOR pathway and alleviating neuronal apoptosis and oxidative stress.