Clinics
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Randomized Controlled Trial
Pharmacotherapy problems in cardiology patients 30 days post discharge from a tertiary hospital in Brazil: a randomized controlled trial.
This is a randomized controlled trial that aims to evaluate the impact of pharmacist-led discharge counseling on reducing pharmacotherapy problems in the 30-day postdischarge period of cardiology patients from a tertiary hospital in Brazil. ⋯ We concluded that pharmacist-led discharge counseling should be an indispensable service, as patients exhibited less pharmacotherapy problems in the 30-day postdischarge period, especially related to drug administration and adherence.
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Randomized Controlled Trial Multicenter Study
Goal-directed therapy in patients with early acute kidney injury: a multicenter randomized controlled trial.
Acute kidney injury is associated with many conditions, and no interventions to improve the outcomes of established acute kidney injury have been developed. We performed this study to determine whether goal-directed therapy conducted during the early stages of acute kidney injury could change the course of the disease. ⋯ Goal-directed therapy for patients in the early stages of acute kidney injury did not change the disease course.
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Randomized Controlled Trial
Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial.
During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity and length of stay of patients in a nosocomial intensive care unit who underwent prophylactic non-invasive ventilation after heart valve replacement. ⋯ Non-invasive ventilation as a therapeutic resource was effective toward improving functionality; however, non-invasive ventilation did not influence the intensive care unit or hospitalization times of the studied cardiac patients.
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Randomized Controlled Trial
The value of high-flow nasal cannula oxygen therapy after extubation in patients with acute respiratory failure.
To investigate the value of high-flow nasal cannula oxygen therapy after extubation in patients with acute respiratory failure. ⋯ At a fixed inspired oxygen fraction, the application of a high-flow nasal cannula after extubation achieves a higher success rate of oxygen therapy and less discomfort at 24h than an air entrainment mask in patients with acute respiratory failure.
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Randomized Controlled Trial
Hyoscine butylbromide for colorectal polyp detection: prospective, randomized, placebo-controlled trial.
The removal of pre-malignant colorectal lesions prevents cancer. Hyoscine has been proposed as a means of improving diagnosis by reducing colonic movements. The aim of this study was to analyze whether this anti-spasmodic enhances the detection of pre-malignant colorectal lesions. ⋯ The use of hyoscine before beginning the withdrawal of the colonoscope does not seem to enhance the PDR and the ADR.