Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
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Randomized Controlled Trial
Effect of intracuff alkalinized 2% lidocaine on endotracheal tube cuff pressure and postoperative throat symptoms in anaesthesia maintained by nitrous oxide.
Aim To compare the effects of endotracheal tube cuff inflation media, air, saline and alkalinized 2% lidocaine on increase of cuff pressure (CP) during nitrous oxide maintained anaesthesia and on incidence of postoperative throat symptoms (PTS), and to evaluate the incidence of postoperative throat mucosal injuries (PTMI) depending on cuff inflation medium. Methods Ninety patients who had undergone elective surgery were randomly allocated into 3 equal groups per cuff inflation media: air (group A), saline (group S) and alkalinized 2% lidocaine (group L). The CP was monitored immediately after cuff inflation and further 5, 15, 30, 60 and 90 minutes after intubation. ⋯ Conclusion The increase of CP contributed to incidence of PTS. The intracuff alkalinized 2% lidocaine was superior to saline and air in the prevention of an increase of CP and reduction of the PTS incidence. There was a strong correlation between the incidence of PTS and PTMI.
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Randomized Controlled Trial
Sedation for transesophageal echocardiography: comparison of propofol, midazolam and midazolam-alfentanil combination.
The administration of trans esophageal echocardiography (TEE) may cause nausea, shortness of breath, agitation, emotional distress and pain in patients due to pharyngo-esophageal intubation, which may be partially relieved by sedoanalgesia. The aim of this study was to compare clinical effects of midazolam, midazolam-alfentanil combination and propofol sedation given for sedation and sedoanalgesia to patients with planned diagnostic TEE interventions. ⋯ During the TEE intervention, the use of propofol, contrary to requirements for additional dose and observation of apnea, appears to be advantageous due to providing more rapid and effective sedation depth without a need of expensive antagonist agents, and allowing early discharge of patients. Additionally, it seems that the use of midazolam combined with alfentanil, is more advantageous comparing to midazolam alone.
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Randomized Controlled Trial Comparative Study
Does epidural clonidine improve postoperative analgesia in major vascular surgery?
To determine the quality and duration of the analgesic and haemodynamic effects of clonidine when used as an additional analgesic for postoperative epidural analgesia in major vascular surgery. ⋯ Under study conditions, clonidine added to morphine, not 0.125% bupivacaine, provided significantly better pain scores at two, six and 24 hours following the start of epidural infusion and the longest-lasting analgesia following the discontinuation of epidural infusion. However, patients from the Group MC were mechanically ventilated longer than patients from other two groups. Continuous monitoring of the patient is necessary after the administration of clonidine for epidural analgesia.
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Randomized Controlled Trial
Efficiency of hypertonic and isotonic seawater solutions in chronic rhinosinusitis.
To compare the efficiency of isotonic and hypertonic seawater solutions used for nasal lavage and quality of life of the patients with chronic rhinosinusitis. ⋯ Hypertonic seawater solution has been proven to be better than isotonic seawater solution in eliminating the symptoms of nasal congestion, rhinorrhea, cough, headache and waking up during the night.