Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
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Ulus Travma Acil Cerrahi Derg · Jan 2024
Evaluation of intestinal necrosis with laser Doppler in experimental mesenteric ischemia model.
Acute mesenteric ischemia (AMI) is responsible for one in a thousand emergency hospital admissions in America and Europe and is associated with high morbidity and mortality rates. Current diagnostic and treatment methods fall short of desired outcomes, often resulting in delayed diagnoses and difficulties in detecting ischemic bowel tissue during treatment. This study evaluates the diagnostic value of commonly used biochemical markers in clinical practice-creatine kinase, C-reactive protein (CRP), and lactate dehydrogenase (LDH)-alongside blood flow measurements using laser Doppler in a rat model of experimental mesenteric ischemia. We also compare these markers with pathological ischemia scoring. ⋯ Creatine kinase and lactate dehydrogenase (LDH) levels may be useful biomarkers in patients with suspected acute mesenteric ischemia (AMI). Blood flow measurements using laser Doppler can accurately identify intestinal loops for resection during surgery.
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Ulus Travma Acil Cerrahi Derg · Jan 2024
[Association of preoperative C-reactive protein to albumin ratio and mortality in elderly patients with hip fractures: A cross-sectional study].
Hip fractures in the elderly have a significant impact, both in terms of human suffering and healthcare costs. Little is known about preoperative markers that may predict mortality following geriatric hip fracture surgery. This study aimed to investigate potential risk factors, including the C-reactive protein to albumin ratio (CAR), for mortality in elderly patients undergoing surgery for hip fracture. ⋯ An elevated preoperative CAR is associated with a significantly increased risk of mortality in elderly patients undergoing hip fracture surgery. Additionally, a shorter time to surgery was associated with lower mortality in these patients.
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Ulus Travma Acil Cerrahi Derg · Jan 2024
The effect of intraperitoneal LR-PRP on bacterial translocation in an experimental model of peritonitis in rats.
This study aims to examine the effect of Leukocyte-Rich Platelet-Rich Plasma (LR-PRP) on bacterial translocation in an experimental peritonitis model in rats. Secondary peritonitis occurs due to the loss of integrity in the mucosal barrier of the gastrointestinal system, resulting from contamination of the peritoneal cavity by microorganisms. LR-PRP has been shown to have positive anti-infectious, immunomodulatory, and angiogenetic effects. ⋯ LR-PRP's ability to suppress bacterial translocation was statistically significant in liver tissue culture, mesenteric lymph node tissue culture, and blood culture when comparing the Control and Experimental groups. LR-PRP was found to be effective in preventing bacterial translocation without suppressing inflammation and exhibited antimicrobial properties as supported by the literature.
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Ulus Travma Acil Cerrahi Derg · Jan 2024
Is there a renal protective role for gelsolin treatment in crush syndrome? An experimental study.
This study aims to investigate the impact of combining crush fluid resuscitation with gelsolin treatment on renal function in a rat model of crush syndrome. ⋯ This study marks the first instance in literature where it has been demonstrated that administering gelsolin along with crush solution does not yield superior results compared to crush solution alone in treating crush syndrome. Nonetheless, further research utilizing varying doses of gelsolin is warranted.
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Ulus Travma Acil Cerrahi Derg · Jan 2024
A new grading system for testicular trauma and one-year follow-up results on male testicular function: Gülhane Grading System.
This study reports our seven-year experience of one-year follow-up results after scrotal and testicular trauma, classified according to the Gülhane Grading System (GGS). We provide detailed hormonal analyses, ultrasound (US) evaluations, and spermiogram results. There are no previous studies that focus on all these detailed topics in relation to a grading system. ⋯ Our new grading system provides a practical and usable grading scale for evaluating scrotal and testicular trauma. Patients with unilateral trauma experienced good recovery, regardless of trauma grade. Bilaterally affected patients, however, were more likely to experience testosterone deficiency and poor spermiogram parameters.