General thoracic and cardiovascular surgery
-
Gen Thorac Cardiovasc Surg · Aug 2011
Case ReportsPatch annulo-aortoplasty in an adult patient with congenital supravalvular aortic stenosis and a small aortic annulus.
A 39-year-old woman with familial homozygous hypercholesterolemia had supravalvular and valvular aortic stenosis. Modified Nick's procedure and aortic valve replacement was performed to relieve both the supravalvular and annular stenoses. ⋯ Histological examination of the aortic cusps showed sclerotic change due to hypercholesterolemia. These findings indicated that familial homozygous hypercholesterolemia caused valvular aortic stenosis and exacerbated congenital supravalvular aortic stenosis.