Journal of cardiovascular computed tomography
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J Cardiovasc Comput Tomogr · Jul 2015
Multicenter Studyβ-Blocker premedication does not increase the frequency of allergic reactions from coronary CT angiography: Results from the Advanced Cardiovascular Imaging Consortium.
β-Blockers are often used for heart rate control during coronary CT angiography (CTA). Increased frequency and severity of allergic reactions to radiocontrast media (RCM) have been reported with concomitant use of β-blockers. ⋯ β-Blocker pretreatment had no effect on the frequency or severity of allergic reaction in patients undergoing coronary CTA, even in patients with a past history of allergy to RCM.
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J Cardiovasc Comput Tomogr · Jan 2015
Randomized Controlled Trial Multicenter StudyQuantification of coronary artery calcium in nongated CT to predict cardiovascular events in male lung cancer screening participants: results of the NELSON study.
To evaluate the incremental prognostic value of the number and maximum volume of coronary artery calcifications over modified Agatston score strata, age, pack-years, and smoking status for predicting cardiovascular events. ⋯ Cardiovascular event rate increased with higher numbers of calcified lesions. The number but not maximum volume of calcifications has independent, although minimal, prognostic value over age, pack-years, smoking status, and modified Agatston score strata in our population.
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J Cardiovasc Comput Tomogr · Jul 2013
Multicenter StudyMultidetector CT predictors of prosthesis-patient mismatch in transcatheter aortic valve replacement.
Prosthesis-patient mismatch (PPM) is a predictor of mortality after aortic valve replacement (AVR). ⋯ PPM is frequent after TAVR. Appropriate annular oversizing does not reduce the rate or severity of PPM. Patient annulus size mismatch, identified by indexed MDCT annular area, is a significant predictor of PPM.
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J Cardiovasc Comput Tomogr · Jul 2012
Randomized Controlled Trial Multicenter Study Comparative StudyCoronary CT angiography versus myocardial perfusion imaging for near-term quality of life, cost and radiation exposure: a prospective multicenter randomized pilot trial.
Clinical outcomes and resource utilization after coronary computed tomography angiography (CTA) versus myocardial perfusion single-photon emission CT (MPS) in patients with stable angina and suspected coronary artery disease (CAD) has not been examined. ⋯ In a pilot randomized controlled trial, patients with stable CAD undergoing coronary CTA and MPS experience comparable improvements in near-term angina-related quality of life. Compared with MPS, coronary CTA evaluation is associated with more aggressive medical therapy, increased coronary revascularization, lower total costs, and lower effective radiation dose.
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J Cardiovasc Comput Tomogr · Sep 2011
Multicenter Study Clinical TrialRationale and design of the DeFACTO (Determination of Fractional Flow Reserve by Anatomic Computed Tomographic AngiOgraphy) study.
Coronary computed tomographic angiography (CTA) allows for noninvasive identification of anatomic coronary artery disease (CAD) severity but does not discriminate whether a stenosis causes ischemia. Computational fluid dynamic techniques applied to CTA images now permit noninvasive computation of fractional flow reserve (FFR), a measure of lesion-specific ischemia, but the diagnostic performance of computed FFR (FFR(CT)) as compared with measured FFR at the time of invasive coronary angiography remains unexplored. ⋯ The DeFACTO study will determine whether the addition of FFR(CT) to conventional CTA improves the diagnosis of hemodynamically significant CAD.