International journal of gynaecology and obstetrics : the official organ of the International Federation of Gynaecology and Obstetrics
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Int J Gynaecol Obstet · Feb 2011
Randomized Controlled Trial Multicenter StudyAdministration of 400 μg of misoprostol to augment routine active management of the third stage of labor.
To assess the effectiveness and safety of the administration of misoprostol, an orally active prostaglandin, in addition to routine uterotonic therapy as part of the active management of the third stage of labor. ⋯ The present study did not confirm a beneficial effect of administering 400 μg of misoprostol, in addition to routine uterotonic therapy, during the third stage of labor, but was consistent with other trials showing a cumulative modest benefit. Where routine uterotonics are available for prophylactic use, any potential benefit of misoprostol might not outweigh the likelihood of adverse effects.
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Int J Gynaecol Obstet · Nov 2010
Randomized Controlled TrialEffects of method of uterine repair on surgical outcome of cesarean delivery.
To compare the rates of intraoperative and postoperative complications of uterine repair when performed in situ or extra-abdominally following cesarean delivery. ⋯ Fewer cases of uterine atony, a shorter operating time, a faster return of bowel function, a lesser need for postoperative analgesics, and lower rates of additional use of postoperative analgesics and wound infections suggest that in-situ uterine repair ought to be preferred to extra-abdominal uterine repair following cesarean delivery.
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Int J Gynaecol Obstet · Oct 2010
Randomized Controlled TrialMetformin compared with glyburide for the management of gestational diabetes.
To assess blood glucose control and neonatal outcomes when women with gestational diabetes mellitus (GDM) were treated with metformin or glyburide. ⋯ The treatment of GDM with metformin or glyburide was found to be equivalent for both women and newborns.
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Int J Gynaecol Obstet · Sep 2010
Randomized Controlled TrialAssessing changes in flow velocimetry and clinical outcome following use of an external aortic compression device in women with postpartum hemorrhage.
To monitor femoral artery blood flow by Doppler velocimetry in women treated for postpartum hemorrhage (PPH) with and without the adjunction of the External Aortic Compression Device (EACD), and to assess the possible adverse effects of the device. ⋯ The EACD contributed safely and effectively to the treatment of 60 women with PPH of different causes.
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Int J Gynaecol Obstet · Apr 2010
Randomized Controlled Trial Comparative StudyRectally administered misoprostol versus intravenous oxytocin infusion during cesarean delivery to reduce intraoperative and postoperative blood loss.
To compare the efficacy of rectally administered misoprostol with intravenous oxytocin infusion in preventing uterine atony and blood loss during cesarean delivery. ⋯ CTRI/2009/091/000075.