Archives of cardiovascular diseases
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Arch Cardiovasc Dis · Apr 2014
Multicenter Study Observational StudyThrombotic and bleeding events after coronary stenting according to clopidogrel and aspirin platelet reactivity: VerifyNow French Registry (VERIFRENCHY).
Dual antiplatelet therapy, comprising aspirin and clopidogrel, is recommended in patients undergoing coronary stenting to avoid the occurrence of stent thrombosis and others ischaemic events. Interindividual response to clopidogrel varies, however, with poor response associated with an increased risk of ischaemic events. New assays are available for testing aspirin and clopidogrel response routinely at the bedside. ⋯ On-treatment platelet reactivity was not associated with 1-year ischaemic or bleeding events in an intermediate-risk population undergoing stent implantation.
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Arch Cardiovasc Dis · Apr 2014
ReviewImaging in pulmonary hypertension: Focus on the role of echocardiography.
Patients with pulmonary hypertension must be evaluated using a multimodality approach to ensure a correct diagnosis and basal evaluation as well as a prognostic assessment. Beyond the assessment of pulmonary pressures, the echocardiographical examination allows the evaluation of right ventricular adaptation to elevated afterload. ⋯ Whereas an isolated change in one echocardiographical variable is not meaningful, multiple echocardiographical variable modifications together provide accurate information. In this review, we will link pulmonary hypertension pathophysiological changes with echocardiographical indices and describe the clinical implications of echocardiographical findings.
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Arch Cardiovasc Dis · Apr 2014
Case ReportsHyperacute flash pulmonary oedema after transcatheter pulmonary valve implantation: The melody of an overwhelmed left ventricle.
Percutaneous transcatheter Melody Valve implantation has achieved standard of care for the management of certain patients with right ventricular outflow tract dysfunction. With its widespread use, some rare and potentially fatal complications, such as right ventricular outflow tract rupture and coronary artery compression, have been reported. We report hyperacute flash pulmonary oedema after Melody Valve implantation for the first time in two patients and describe some possible predictors.