JACC. Cardiovascular interventions
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JACC Cardiovasc Interv · Apr 2010
Percutaneous pulmonary valve implantation in the young 2-year follow-up.
The aim of this study was to investigate physiological and clinical consequences of percutaneous pulmonary valve implantation (PPVI) in patients with chronic right ventricular outflow tract (RVOT) obstruction and volume overload. ⋯ Percutaneous pulmonary valve implantation is feasible and safe in the young with dysfunctional RVOT conduits. An improvement in symptoms, hemodynamic status, and objective findings of exercise performance occurs. Early follow-up demonstrates persistent improvement in ventricular parameters, PR, and objective exercise capacity.
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JACC Cardiovasc Interv · Mar 2010
Randomized Controlled Trial Multicenter Study Comparative StudyPrior coronary artery bypass graft patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention.
We sought to compare outcomes in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) with or without previous coronary artery bypass grafts (CABG). ⋯ Prior CABG patients with STEMI are less likely to undergo acute reperfusion, have worse angiographic outcomes following primary PCI, and higher 90-day mortality. These findings are especially applicable when the IRA was a bypass graft.
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JACC Cardiovasc Interv · Mar 2010
Randomized Controlled Trial Multicenter Study Comparative StudyEfficacy of high-dose atorvastatin loading before primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: the STATIN STEMI trial.
This study sought to determine the efficacy of high-dose atorvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). ⋯ High-dose atorvastatin pre-treatment before PCI did not show a significant reduction of MACEs compared with low-dose atorvastatin but did show improved immediate coronary flow after primary PCI. High-dose atorvastatin may produce an optimal result for STEMI patients undergoing PCI by improving microvascular myocardial perfusion. (Efficacy of High-Dose AtorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction [STATIN STEMI]; NCT00808717).
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JACC Cardiovasc Interv · Mar 2010
Indications and outcomes of surgical closure of ventricular septal defect in adults.
We sought to review our experience with surgical ventricular septal defect (VSD) closure in adults. ⋯ Associated heart defects and AR were common indications for VSD closure in adults, which was performed with low mortality and morbidity. Patch closure and use of intraoperative transesophageal echocardiography improve surgical outcomes. Important residua emphasize the need for life-long informed follow-up.