JACC. Cardiovascular imaging
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JACC Cardiovasc Imaging · Oct 2015
Randomized Controlled Trial Multicenter StudySeverity of Remodeling, Myocardial Viability, and Survival in Ischemic LV Dysfunction After Surgical Revascularization.
This study sought to test the hypothesis that end-systolic volume (ESV), as a marker of severity of left ventricular (LV) remodeling, influences the relationship between myocardial viability and survival in patients with coronary artery disease and LV systolic dysfunction. ⋯ Among patients with ischemic cardiomyopathy, those with greater LV ESVI and no substantial viability had worse prognosis. However, the effect of CABG relative to medical therapy was not differentially influenced by the combination of these 2 factors. Lower ESVI did not identify patients in whom myocardial viability predicted better outcome with CABG relative to medical therapy. (Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease [STICH]; NCT00023595).
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JACC Cardiovasc Imaging · Oct 2015
Coronary Artery Axial Plaque Stress and its Relationship With Lesion Geometry: Application of Computational Fluid Dynamics to Coronary CT Angiography.
The purpose of this study was to characterize the hemodynamic force acting on plaque and to investigate its relationship with lesion geometry. ⋯ APS uniquely characterizes the stenotic segment and has a strong relationship with lesion geometry. Clinical application of these hemodynamic and geometric indices may be helpful to assess the future risk of plaque rupture and to determine treatment strategy for patients with coronary artery disease. (Evaluation of FFR, WSS, and TPF Using CCTA; NCT01857687).
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JACC Cardiovasc Imaging · Sep 2015
Multicenter StudyLV Mass as a Predictor of CVD Events in Older Adults With and Without Metabolic Syndrome and Diabetes.
The purpose of this study was to examine the prognostic significance of left ventricular (LV) mass for cardiovascular disease (CVD) events in older adults with and without metabolic syndrome (MetS) and diabetes mellitus (DM). ⋯ LV mass is associated with increased CVD risk and provides modest added prediction and clinical utility compared to standard risk factors in older persons with and without MetS but not with DM.
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JACC Cardiovasc Imaging · Sep 2015
Comparative StudyAssessment of Post-Procedural Aortic Regurgitation After TAVR: An Intraprocedural TEE Study.
The purpose of this study was to determine which echocardiographic parameters, including holodiastolic flow reversal (HDFR) in the descending aorta, were useful for grading of post-procedural aortic regurgitation (PAR) after transcatheter aortic valve replacement (TAVR) using intraprocedural transesophageal echocardiography. ⋯ The presence of consistent HDFR and jet extent beyond the tip of AML are indicative of significant PAR after TAVR.