Injury
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This article is concerned with the search for threshold values for bone quality beyond which the risk of fixation failure increased. For trochanteric fractures we recognized a BMD lower than 250mg/cm(3) as an additional risk for cut out. For medial femoral neck fractures since joint replacement surgery is available and produces excellent functional results, we see no indication for further differentiation or analysis of bone quality in relation to fracture fixation. ⋯ For proximal humerus fractures, BMD value of 95mg/cm(3) could be seen as a threshold value below which the risk of failure rises markedly. In relation to osteoporotic distal radius fractures, based on our clinical experience and scientific analyses there are virtually no restrictions as far as bone quality is concerned on the application of palmar locking implants in the surgical management of distal radius fractures. Optimization of preoperative diagnostics might help to revise the treatment algorithm to take bone density into account, thus reducing the risk of failure and, at the same time, acquiring additional data for future reference.
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The management of complex tibial plateau fractures is ever evolving. The severity of the injury to the surrounding soft tissues influences the timing and the method of fixation. ⋯ Locking plates, conventional plates and fine wire fixators all have been used successfully with satisfactory outcomes. In this article we report on the latest advances made in the management of these complex injuries.
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The aim of this study was to review the complication rate and profile associated with surgical fixation of acute midshaft clavicle fracture in a large cohort of patients treated in a level I trauma centre. ⋯ Intramedullary fixation of midshaft clavicle fracture is associated with a higher incidence of complications. Plate fixation is associated with a higher rate of symptomatic metalware requiring removal compared to intramedullary fixation. Approximately one in three complications may be avoided by attention to adequate surgical technique.
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The intention of the current work is to assess new bone formation and degradation behavior of nanocrystalline hydroxyapatite with (HA/col-1) or without collagen-type I (HA) in osteoporotic metaphyseal bone defects in goats. After ovariectomy and special low-calcium diet for three months, 3 drill hole defects in the vertebrae of L3, L4, L5, 4 drill hole defects in the right and left iliac crest and 1 drill hole defect at the distal femur were created in three Chinese mountain goats with a total of 24 defects. The defects were either filled with one of the biomaterials or left empty (empty defect control group). ⋯ Histology revealed a good biocompatibility without inflammatory reaction for the HA- and HA/col-1 implants with a higher fragmentation of the HA-implant compared to the HA/col-1 biomaterial and formation of new bone in the region between the biomaterial fragments by osteoblasts. Fragmentation was shown by transmission electron microscopy to be caused by multinuclear osteoclast-like cells with degradation of the implant via intracellular incorporation of degraded implant material particles. In conclusion, both nanoparticulate HA with and without collagen type-1 showed better new bone formation compared to untreated drill hole defects in metaphyseal regions of this osteoporotic Chinese mountain goat model with good biocompatibility.