Injury
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Fracture healing outcome is to a great extent steered by the mechanical environment. The importance of early phase mechanical fracture stimulation is still controversially discussed, both clinically and scientifically. Furthermore, the role of fracture activity, defined as the number of stimulatory events per time, is particularly for the direct postoperative phase unknown. ⋯ The data demonstrates a positive effect of, within limits, frequent fracture stimulation on bone healing and suggests the importance of the mechanical environment in the direct post-operative healing phase. Clinically, the findings may advocate for the concept of direct post-operative weight bearing. This, however, requires clinical validation and must be considered within the full clinical context including the risk for fixation failure from overloading.
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Randomized Controlled Trial Multicenter Study Retracted Publication
A Multicentre Randomized Controlled Trial Comparing Plating with Intramedullary Nailing for Extra-articular Distal Tibial Fractures.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). Injury was alerted to concerns regarding similarities of the data of this study to those published in the FixDIT UK trial.1 The investigators were invited to reply to the issues raised and were also asked to provide their original dataset available to the Editor-in-Chief. ⋯ Costa ML, Achten J, Griffin J, Petrou S, Pallister I, Lamb SE, Parsons NR; FixDT Trial Investigators Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Trial.. JAMA. 2017 Nov 14;318(18):1767-1776.