The journal of trauma and acute care surgery
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J Trauma Acute Care Surg · Nov 2013
Comparative StudyExtracorporeal life support in patients with multiple injuries and severe respiratory failure: a single-center experience?
The use of extracorporeal life support in trauma casualties is limited by concerns regarding hemorrhage, particularly in the presence of traumatic brain injury (TBI). We report the use of extracorporeal membrane oxygenation (ECMO)/interventional lung assist (iLA) as salvage therapy in trauma patients. High-flow technique without anticoagulation was used in patients with coagulopathy or TBI. ⋯ Therapeutic study, level V.
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J Trauma Acute Care Surg · Nov 2013
Comparative StudyIncidental findings in patients with multiple injuries: how to proceed?
Multislice computed tomography (MSCT) is the diagnostic criterion standard for the initial evaluation of patients with suspected multiple injuries. Besides scanning for injuries directly related to the initial trauma, MSCT scans can reveal pathologies unrelated to the trauma of clinical relevance.The aim of the present study was to determine the frequency and follow-up course of incidental findings in patients with multiple injuries. ⋯ Epidemiologic study, level III.
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J Trauma Acute Care Surg · Nov 2013
Comparative StudySurgical management of traumatic isolated sternal fracture and manubriosternal dislocation.
The aim of this study was to evaluate the surgical procedures of osteosynthesis and the respective costs in isolated sternal fractures and manubriosternal dislocations. ⋯ Therapeutic study, level IV; economic analysis, level IV.
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J Trauma Acute Care Surg · Nov 2013
Comparative StudyTraumatic brain injury-induced alterations in peripheral immunity.
The complex alterations that occur in peripheral immunity after traumatic brain injury (TBI) have been poorly characterized to date. The purpose of this study was to determine the temporal changes in the peripheral immune response after TBI in a murine model of closed head injury. ⋯ TBI results in temporal changes in both the peripheral and the central immune systems culminating in an overall immune suppressed phenotype and anti-inflammatory milieu.