Medizinische Klinik, Intensivmedizin und Notfallmedizin
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Med Klin Intensivmed Notfmed · Jun 2013
[Glucose control in the critically ill. Innovations and contemporary strategies].
Glucose control should be part of standard therapy in intensive care units (ICU) due to the proven association of hyperglycemia with increased morbidity and mortality. Due to the results of the latest randomized controlled multicentre trials blood glucose target levels of 140-180 mg/dl are currently recommended. In critically ill patients glucose monitoring should not be performed using point of care (POC) devices because of inacceptable inaccuracies. ⋯ Besides mean glucose levels, glucose variability and glucose complexity are also associated with outcome in critically ill patients and might therefore be future target parameters. Critically ill diabetic patients might benefit from different glucose target levels depending on the preadmission glucose control. Hypoglycemic events <80 mg/dl should be avoided because of the association with poor outcome.