Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Aug 2013
Comparative StudyBiological and electrophysiologic effects of poly(3,4-ethylenedioxythiophene) on regenerating peripheral nerve fibers.
Uninjured peripheral nerves in upper-limb amputees represent attractive sites for connectivity with neuroprostheses because their predictable internal topography allows for precise sorting of motor and sensory signals. The inclusion of poly(3,4-ethylenedioxythiophene) reduces impedance and improves charge transfer at the biotic-abiotic interface. This study evaluates the in vivo performance of poly(3,4-ethylenedioxythiophene)-coated interpositional decellularized nerve grafts across a critical nerve conduction gap, and examines the long-term effects of two different poly(3,4-ethylenedioxythiophene) formulations on regenerating peripheral nerve fibers. ⋯ Both poly(3,4-ethylenedioxythiophene) formulations were compatible with peripheral nerve regeneration at 3 months. This study supports poly(3,4-ethylenedioxythiophene) as a promising adjunct for peripheral nerve interfaces for prosthetic control and other biomedical applications because of its recognized ionic-to-electronic coupling potential.
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Plast. Reconstr. Surg. · Aug 2013
Free-style local perforator flaps: versatility of the v-y design to reconstruct soft-tissue defects in the skin cancer population.
Free-style local perforator flaps can be harvested from any region of the body where an appropriate and detectable perforator vessel is present. Their use allows the surgeon to perform a "like with like" reconstruction by mobilizing surrounding tissues on a consistent vascular source. The authors report their experience with V-Y free-style perforator flaps in reconstruction of soft-tissue defects subsequent to skin cancer excision. ⋯ Therapeutic, IV.
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Plast. Reconstr. Surg. · Jul 2013
Randomized Controlled Trial Comparative StudyProspective randomized controlled trial: fibrin sealant reduces split skin graft donor-site pain.
Pain at split skin graft donor sites is common. Fibrin sealant has been demonstrated to reduce time to hemostasis at wound sites, and patients receiving this treatment were incidentally noted to report less pain. This study aimed to evaluate pain and incapacity in split skin graft donor sites treated with and without fibrin sealant. ⋯ Therapeutic, II.