Seminars in arthritis and rheumatism
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Semin. Arthritis Rheum. · Oct 2012
ReviewMagnetic resonance imaging of subchondral bone marrow lesions in association with osteoarthritis.
This nonsystematic literature review provides an overview of magnetic resonance imaging (MRI) of subchondral bone marrow lesions (BMLs) in association with osteoarthritis (OA), with particular attention to the selection of MRI sequences and semiquantitative scoring systems, characteristic morphology, and differential diagnosis. Histologic basis, natural history, and clinical significance are also briefly discussed. ⋯ Subchondral BMLs are a common imaging feature of OA with clinical significance and typical signal alteration patterns, which can be assessed and graded by semiquantitative scoring systems using sensitive MRI sequences.
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Semin. Arthritis Rheum. · Feb 2012
ReviewPsychological factors affecting the outcome of total hip and knee arthroplasty: a systematic review.
Recently, numerous studies have reported that psychological factors can influence the outcome of total knee arthroplasty (TKA) and total hip arthroplasty (THA). However, a systematic overview is missing. The objective of this study was to examine which psychological factors influence the outcome of TKA and THA and to what extent. ⋯ Low preoperative mental health and pain catastrophizing have an influence on outcome after TKA. With regard to the influence of other psychological factors and for hip patients, only limited, conflicting, or no evidence was found.
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Semin. Arthritis Rheum. · Feb 2012
ReviewCentral sensitization in patients with rheumatoid arthritis: a systematic literature review.
The goal of the present study is to systematically review the scientific literature addressing central sensitization and central nociceptive processing in patients with rheumatoid arthritis (RA). ⋯ The symmetrical manifestation of the disease, the poor relation between disease activity and symptoms, and the generalized hyperalgesia at both articular and nonarticular sites for different kinds of stimuli are indicative of the presence of central sensitization in RA patients. Further research is required to provide firm evidence in support of various aspects of central sensitization in humans with RA.
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Semin. Arthritis Rheum. · Dec 2011
ReviewA systematic review and mixed treatment comparison of the efficacy of pharmacological treatments for fibromyalgia.
To review the literature on pharmacological treatments for fibromyalgia. ⋯ The current study confirms the therapeutic efficacy of pregabalin and the SNRIs, duloxetine and milnacipran, in the treatment of fibromyalgia. Given their different modes of action, combination therapy with pregabalin plus an SNRI should be investigated in future research.
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Semin. Arthritis Rheum. · Dec 2011
ReviewNew concepts in pain research and pain management of the rheumatic diseases.
To provide an update on advances in pain research and practical guidelines for pain management in the rheumatic diseases. ⋯ Fibromyalgia and other forms of chronic widespread pain have taught us important lessons about pain epidemiology and pain pathways.