Anesthesia and analgesia
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Anesthesia and analgesia · Apr 2007
Comparative StudySevoflurane affects neurogenesis after forebrain ischemia in rats.
The effect of sevoflurane on the neuroregenerative potential after neuronal injury is unclear. We investigated the effect of low and high concentrations of sevoflurane on endogenous neurogenesis after cerebral ischemia. ⋯ The present data suggest that high concentrations of sevoflurane stimulate neurogenesis in the dentate gyrus after cerebral ischemia.
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Anesthesia and analgesia · Apr 2007
Intravenous mononuclear marrow cells reverse neuropathic pain from experimental mononeuropathy.
Stem cells mediate neuroprotection in a variety of nervous system injury models. In this study, we evaluated a potential role for stem cells in pain therapies. Marrow mononuclear cells containing mixed stem cell populations were used because of wide experience with these cells in experimental and clinical transplantation. ⋯ These studies suggest that stem or progenitor cell-mediated therapies may be useful for the treatment of pain after nerve injury, and deserve further study to elucidate the mechanisms of analgesia.
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Anesthesia and analgesia · Apr 2007
Editorial CommentOptimal care for patients who are Jehovah's Witnesses.