Anesthesia and analgesia
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Anesthesia and analgesia · Apr 2008
A new single use supraglottic airway device with a noninflatable cuff and an esophageal vent: an observational study of the i-gel.
The i-gel is a new single-use supraglottic airway device with a noninflatable cuff and an esophageal vent. ⋯ The i-gel is a reliable, easily inserted airway device that provides an adequate seal with a low morbidity rate.
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Anesthesia and analgesia · Apr 2008
Upregulation of dorsal horn microglial cyclooxygenase-1 and neuronal cyclooxygenase-2 after thoracic deep muscle incisions in the rat.
Plantar hindpaw incision produces hyperalgesia, transient upregulation of cyclooxygenase-2 (COX-2) and prolonged upregulation of cyclooxygenase-1 (COX-1) in rat lumbar spinal cord. Our hypothesis in this study was that a deep thoracic incision causes COX-1 and COX-2 upregulation in the dorsal horn coincident with pain-related behavior, and that specific cell types contribute to this increase in COX expression. ⋯ A unilateral deep thoracic wound produces pain-related behavior and, at the same time, ipsilateral upregulation of microglial COX-1 and neuronal COX-2 in the thoracic dorsal horn.
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Anesthesia and analgesia · Apr 2008
Comment Letter Case ReportsCould this be malignant hyperthermia?
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Anesthesia and analgesia · Apr 2008
Randomized Controlled TrialA prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes.
Total knee arthroplasty (TKA) is associated with considerable postoperative pain, which, if unrelieved, may result in prolonged hospital stay, inability to participate in rehabilitation programs, poor outcomes, and greater use of healthcare resources. The hypothesis of this study is that perioperative administration of celecoxib will improve analgesic efficacy, with a resultant improvement in short- and long-term clinical outcomes after TKA. ⋯ Perioperative use of celecoxib reduces postoperative pain, opioid consumption, opioid-related adverse effects, and is associated with long-term benefits including improved knee function and less time to achieve effective knee ROM after TKA.