Anesthesia and analgesia
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Anesthesia and analgesia · Nov 2009
Editorial CommentOn cricoid pressure: "may the force be with you".
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Anesthesia and analgesia · Nov 2009
Randomized Controlled Trial Comparative StudyA comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
Gabapentin and ketamine are popular analgesic adjuvants for improving perioperative pain management. We designed this double-blind, placebo-controlled study to test and compare the preventive effects of perioperative ketamine and gabapentin on early and chronic pain after elective hysterectomy. ⋯ Gabapentin and ketamine are similar in improving early pain control and in decreasing opioid consumption; however, gabapentin also prevented chronic pain in the first 6 postoperative months.
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Anesthesia and analgesia · Nov 2009
Randomized Controlled TrialEarly cognitive impairment after sedation for colonoscopy: the effect of adding midazolam and/or fentanyl to propofol.
The sedative drug combination that produces minimal cognitive impairment and optimal operating conditions during colonoscopy has not been determined. We sought to determine if the use of propofol alone results in less cognitive impairment at discharge than the use of propofol plus midazolam and/or fentanyl in patients presenting for elective outpatient colonoscopy. ⋯ Significant cognitive impairment was common at discharge from elective outpatient colonoscopy. However, the addition of midazolam and/or fentanyl to propofol sedation did not result in more cognitive impairment than the use of propofol alone. Furthermore, the use of adjuvants improved the ease of colonoscopy without increasing the rate of complications or prolonging early recovery times..