Anesthesia and analgesia
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Anesthesia and analgesia · May 2009
Case ReportsPostoperative intensive care unit drug fever caused by dexmedetomidine.
Dexmedetomidine hydrochloride is a potent, highly selective alpha-2 adrenergic receptor agonist, broadly used as a sedative drug in intensive care units. We describe the case of a 59-yr-old patient who experienced drug fever caused by dexmedetomidine hydrochloride. ⋯ This symptom improved rapidly 7 h after stopping dexmedetomidine hydrochloride. Other possible causes (such as infection) were sequentially eliminated.
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Anesthesia and analgesia · May 2009
The effects of platelet transfusions evaluated using rotational thromboelastometry.
In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. ⋯ Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in these patients.
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Anesthesia and analgesia · May 2009
Case ReportsAnesthetic management of seven deliveries in three sisters with the May-Hegglin anomaly.
May-Hegglin anomaly is a rare genetic hematological disorder characterized by thrombocytopenia, but platelet function is usually normal. Three sisters with May-Hegglin anomaly and thrombocytopenia (platelet counts 14,000-100,000/mm(3)) were given neuraxial anesthesia for a total of 7 deliveries, 5 vaginal and 2 cesarean. None of the women had complications and no blood products were transfused.
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Anesthesia and analgesia · May 2009
An anatomical study of the parasacral block using magnetic resonance imaging of healthy volunteers.
The parasacral approach to sciatic blockade is reported to be easy to learn and perform, with a high success rate and few complications. ⋯ These findings question the reliability of the anatomical landmarks of the parasacral block and raise the possibility of frequent visceral puncture using this technique.
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Anesthesia and analgesia · May 2009
The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor.
CDP-choline (citicholine; cytidine-5'-diphosphate choline) is an endogenously produced nucleotide which, when injected intracerebroventricularly, exerts an antinociceptive effect in acute pain models mediated by central cholinergic mechanisms and alpha7 nicotinic acetylcholine receptors (alpha7nAChR). Previous reports also suggest that the peripheral cholinergic system has an antiinflammatory role mediated by alpha7nAChRs on macrophages. ⋯ The results of this study suggest that intraplantar CDP-choline has antihypersensitivity and antiinflammatory effects mediated via alpha7nAChRs in the carrageenan-induced inflammatory pain model.