Anesthesia and analgesia
-
Anesthesia and analgesia · Nov 2012
Randomized Controlled TrialThe effect of perioperative intravenous lidocaine and ketamine on recovery after abdominal hysterectomy.
Perioperative ketamine infusion reduces postoperative pain; perioperative lidocaine infusion reduces postoperative narcotic consumption, speeds recovery of intestinal function, improves postoperative fatigue, and shortens hospital stay. However, it is unknown whether perioperative IV lidocaine and/or ketamine enhances acute functional recovery. We therefore tested the primary hypothesis that perioperative IV lidocaine and/or ketamine in patients undergoing open abdominal hysterectomy improves rehabilitation as measured by a 6-minute walk distance (6-MWD) on the second postoperative morning. ⋯ Our results do not support use of lidocaine or ketamine for improving 6-MWD on the second postoperative day after open hysterectomy.