Anesthesia and analgesia
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Anesthesia and analgesia · Oct 2013
Comparative StudyThe Hemodynamic Response to Dexmedetomidine Loading Dose in Children With and Without Pulmonary Hypertension.
Dexmedetomidine, an α-2 receptor agonist, is widely used in children with cardiac disease. Significant hemodynamic responses, including systemic and pulmonary vasoconstriction, have been reported after dexmedetomidine administration. Our primary goal of this prospective, observational study was to quantify the effects of dexmedetomidine initial loading doses on mean pulmonary artery pressure (PAP) in children with and without pulmonary hypertension. ⋯ Dexmedetomidine initial loading doses were associated with significant systemic vasoconstriction and hypertension, but a similar response was not observed in the pulmonary vasculature, even in children with pulmonary hypertension. Dexmedetomidine does not appear to be contraindicated in children with pulmonary hypertension.
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Anesthesia and analgesia · Oct 2013
Biography Historical ArticleThomas Linwood Bennett, MD: One of New York City's First Prominent Physician Anesthetists.
Thomas Linwood Bennett (1868-1932) was one of New York City's first prominent physician anesthetists. He was the first dedicated anesthetist at the Hospital for the Ruptured and Crippled, subsequently renamed Hospital for Special Surgery. He subsequently practiced at multiple institutions throughout New York City as one of the first physicians in the United States to dedicate his entire practice to the emerging field of anesthesia. Bennett was considered the preeminent anesthetist of his time, excelling at research, innovation, education, and clinical care.
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Anesthesia and analgesia · Oct 2013
Comparative StudyNeuraxial Anesthesia Decreases Postoperative Systemic Infection Risk Compared with General Anesthesia in Knee Arthroplasty.
This large, retrospective observational study found that neuraxial anaesthesia was associated with a significantly lower risk of both pneumonia (OR 0.51) and composite systemic infection (OR 0.77) than general anaesthesia in patients undergoing knee arthroplasty.
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