Anesthesia and analgesia
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Anesthesia and analgesia · Oct 2015
Editorial Comparative StudyDavid (Propofol Wannabes) Versus Goliath (Propofol): AZD-3043 Goes Up Against the Giant!
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Anesthesia and analgesia · Oct 2015
Editorial"You Live Life Going Forwards and Understand It Looking Backwards!" The Sixtieth Anniversary of the World Federation of Societies of Anaesthesiologists: 60 Years of Cooperation Between the International Anesthesia Research Society and the World Federation of Societies of Anaesthesiologists.
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Anesthesia and analgesia · Oct 2015
Randomized Controlled Trial Comparative StudyConventional Landmark-Guided Midline Versus Preprocedure Ultrasound-Guided Paramedian Techniques in Spinal Anesthesia.
Multiple passes and attempts while administering spinal anesthesia are associated with a greater incidence of postdural puncture headache, paraesthesia, and spinal hematoma. We hypothesized that the routine use of a preprocedural ultrasound-guided paramedian technique for spinal anesthesia would reduce the number of passes required to achieve entry into the subarachnoid space when compared with the conventional landmark-guided midline approach. ⋯ Routine use of paramedian spinal anesthesia in the orthopedic patient population undergoing joint replacement surgery, guided by preprocedure ultrasound examination, significantly decreases the number of passes and attempts needed to enter the subarachnoid space.
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Anesthesia and analgesia · Oct 2015
ReviewClinical Research Methodology 1: Study Designs and Methodologic Sources of Error.
Clinical research can be categorized by the timing of data collection: retrospective or prospective. Clinical research also can be categorized by study design. ⋯ Comparative clinical trials are prospective cohort studies that compare treatments assigned to patients by the researchers. Most errors in clinical research findings arise from 5 largely distinguishable classes of methodologic problems: selection bias, confounding, measurement bias, reverse causation, and excessive chance variation.