Anesthesia and analgesia
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The delivery performance of two Fortec vaporizers for isoflurane in oxygen (O2) was evaluated. Isoflurane concentration was measured at a constant O2 flow rate (from 0.75 to 15 L/min) as the vaporizer dial setting was changed over the range of 0% to 5%. At vaporizer dial settings of 2% or less the average delivered isoflurane concentration differed from dial settings by less than 0.25 vol% at all O2 flows. ⋯ Increasing the environmental temperature to 30 degrees C or decreasing it to 15 degrees C increased or decreased, respectively, vaporized output when compared with conditions at 22 degrees C. Little or no effect on vaporizer output was noted with simulated positive pressure ventilation up to a breathing circuit pressure of 25 torr. We conclude the Fortec vaporizer is as efficient in delivering isoflurane in O2 as previous reports have shown the Fluotec Mark III to be in its delivery of halothane.
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Of 55 abstracts presented at the 1979 annual meeting of the International Anesthesia Research Society (I. A. R. ⋯ S. abstracts were filed in Science Citation Index (SCI) as cited reference and by January 1, 1981, fifty-six 1979 A. S. A. abstracts were filed.
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Anesthesia and analgesia · May 1982
Use of 100-Hertz tetanus as an index of recovery from pancuronium-induced non-depolarizing neuromuscular blockade.
During recovery from non-depolarizing neuromuscular blockade the evoked response to train-of-four (TOF), 100-HZ tetanus (T100) and 50-HZ tetanus (T50) was measured in 10 patients. When the TOF fade ratio exceeded 0.70, tetanic tension to T50 was well sustained. ⋯ T100 stimulation appears to be too sensitive a test to residual curarization for routine clinical use. Fade on T100 may be quite apparent at a time when the use of additional neuromuscular antagonists are not indicated and may be counterproductive.
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Anesthesia and analgesia · May 1982
Epinephrine-induced arrhythmias during halothane anesthesia with the addition of nitrous oxide, nitrogen, or helium in dogs.
The arrhythmogenicity of epinephrine was examined in 34 male mongrel dogs awake and during 1.1 MAC steady state halothane-O2 anesthesia with the addition of 50% N2O, nitrogen, or helium. All anesthetized dogs required more epinephrine than did awake dogs to produce ventricular extrasystoles. ⋯ The dogs given halothane-N2O also showed a small, but statistically significant difference from dogs given halothane-O2. These results suggest that the addition of N2O to halothane increases the cardiac arrhythmic potential of epinephrine in the dog.