Anesthesia and analgesia
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Anesthesia and analgesia · Oct 1986
Comparative StudyComparison of resuscitation of sheep and dogs after bupivacaine-induced cardiovascular collapse.
This study evaluated interspecies sensitivity and ability to resuscitate pentobarbital anesthetized sheep and dogs after cardiovascular toxic doses of bupivacaine. Every minute, 3 mg/kg of bupivacaine was injected into the right atrium over the course of 10 sec until cardiovascular collapse occurred. While the bupivacaine was given, the animals were made apneic for 90 sec and then ventilated with 100% oxygen. ⋯ All dogs could be resuscitated after two additional cardiovascular collapses induced by bupivacaine, but no sheep could be resuscitated after a second cardiovascular collapse. Concentrations of bupivacaine in cardiac tissue and serum levels of bupivacaine after the last resuscitation attempt were significantly greater in the dogs than in the sheep. We conclude that sheep are more sensitive to bupivacaine than dogs, but that even sheep can be resuscitated after cardiovascular collapse produced by bupivacaine.
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Anesthesia and analgesia · Sep 1986
Epidural analgesic techniques in the management of cervical pain.
The injection of depot steroids into the cervical epidural space can maximize the conservative management of patients with cervical radiculopathy. We retrospectively studied 25 patients with cervical radiculopathy who received a total of 45 epidural injections of steroids. ⋯ The patient's history and a description of the pain and the corresponding neurological abnormalities present were of value in the selection of patients who were most likely to respond favorably to epidural steroids, whereas laboratory studies were not as useful. Anesthesiologists, many already familiar with the use of epidural steroid injection in the treatment of low back pain, should add to their armamentarium the use of such techniques in the management of patients with acute and chronic cervical radiculopathy.